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Moreover, the indole core is substituted at R3 that has a carbonyl team and that is also bonded to some napthalene moeity. Napthalene is often a bicyclic construction of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it like a ketone. JWH-018 is an analog of THJ-018, in which the core indazole construction is substituted with a